‘fill me from crown tother toe top-flight of driest cruelty!Make thick my blood’ I think this means that lady macbeth(lm)wants to get ready to challenge someone verbally,  ‘stop the access and passage of remorse ‘ this again I think it means her character generally finds it hard to be cruel and is getting in mind set to be harsh, ‘ I may pour my spirits in thy ear’ I thing that lm wants to pour her words in to her husbands ear e.g help him.